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| Untersuchte Arbeit: Seite: 15, Zeilen: 5-13 |
Quelle: Bryder_et_al_2006 Seite(n): 339, Zeilen: figure |
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Figure 1.2.2: A model of the haematopoietic developmental hierarchy. Self-renewing HSCs reside at the top of the hierarchy, thereby giving rise to a number of multipotent progenitors. Multipotent progenitors give rise to oligo-potent progenitors including the CLP, which gives rise to mature B lymphocytes, T lymphocytes, and natural killer (NK) cells. The common myeloid progenitor (CMP) gives rise to granulocyte-macrophage progenitors, which differentiate into monocytes/macrophages and granulocytes, and megakaryocyte/erythrocyte progenitors, which differentiate into megakaryocytes/platelets and erythrocytes. The cell surface phenotype of many of these cell types is shown for the murine and human systems 50(Figure adapted from Bryder D et al., 2006). 50. Bryder D, Rossi DJ, Weissman IL. Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol. 2006;169:338-346. |
Figure 1. Model of the hematopoietic developmental hierarchy. Self-renewing HSCs reside at the top of the hierarchy, giving rise to a number of multipotent progenitors. Multipotent progenitors give rise to oligo-potent progenitors including the CLP, which gives rise to mature B lymphocytes, T lymphocytes, and natural killer (NK) cells. The common myeloid progenitor (CMP) gives rise to granulocyte-macrophage progenitors, which differentiate into monocytes/macrophages and granulocytes, and megakaryocyte/erythrocyte progenitors, which differentiate into megakaryocytes/platelets and erythrocytes. Both CMPs and CLPs have been proposed to give rise to dendritic cells. The cell surface phenotype of many of these cell types is shown for the murine and human systems. |
The figure is sufficiently referenced, but it is not clear to the reader that the entire figure caption is also taken verbatim from the source. |
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