FANDOM


Reconsolidation: Behavioural and Electrophysiological Sequelae of Context and Stress in Human Episodic Memory

von Dr. Jennifer L. Moore

vorherige Seite | zur Übersichtsseite | folgende Seite
Statistik und Sichtungsnachweis dieser Seite findet sich am Artikelende
[1.] Jm/Fragment 004 05 - Diskussion
Zuletzt bearbeitet: 2014-02-20 00:17:35 Schumann
Fragment, Gesichtet, Jm, SMWFragment, Schutzlevel sysop, Verschleierung, Wang et al 2008

Typus
Verschleierung
Bearbeiter
Hindemith
Gesichtet
Yes
Untersuchte Arbeit:
Seite: 4, Zeilen: 5-8
Quelle: Wang et al 2008
Seite(n): 5602, Zeilen: r.col: 2ff
Using drug cues as reinforcers, investigators reported that the β-adrenoreceptor antagonist propranolol, administered after reactivation of cocaine or morphine conditioned place preference (CPP), impairs drug seeking via disruption of reconsolidation (Bernardi et al., 2006; Robinson & Franklin, 2007). Using drugs as reinforcers, investigators reported that the β-adrenoreceptor antagonist propranolol, administered after reactivation of cocaine or morphine conditioned place preference (CPP), impairs drug seeking via disruption of reconsolidation (Bernardi et al., 2006; Robinson and Franklin, 2007).
Anmerkungen

The source is not mentioned here.

Sichter
(Hindemith) Agrippina1

[2.] Jm/Fragment 004 10 - Diskussion
Zuletzt bearbeitet: 2014-01-13 07:45:34 Graf Isolan
BauernOpfer, Fragment, Gesichtet, Jm, Lee et al 2005, SMWFragment, Schutzlevel sysop

Typus
BauernOpfer
Bearbeiter
Graf Isolan
Gesichtet
Yes
Untersuchte Arbeit:
Seite: 4, Zeilen: 10-19
Quelle: Lee et al 2005
Seite(n): 795, Zeilen: left col. 14-28
Lee and colleagues (2005) found that infusions of Zif268 antisense oligodeoxynucleotides into the basolateral amygdala of rats, prior to the reactivation of a well-learned memory for a conditioned stimulus (CS)-cocaine association, abolished the acquired conditioned reinforcing properties of the drug-associated stimulus and thus its impact on the learning of a new cocaine-seeking response. Furthermore, it was shown that reconsolidation of CS-fear memories also requires Zif268 in the amygdala. These results demonstrate that appetitive CS-drug memories undergo reconsolidation in a manner similar to aversive memories and that this amygdala-dependent reconsolidation can be disrupted to reduce the impact of drug cues on drug seeking.

Lee, J.L., Di Ciano, P., Thomas, K.L., & Everitt, B.J. (2005). Disrupting reconsolidation of drug memories reduces cocaine-seeking behaviour. Neuron, 47, 795-801.

Here, we show that infusion of Zif268 antisense oligodeoxynucleotides into the basolateral amygdala, prior to the reactivation of a well-learned memory for a conditioned stimulus (CS)-cocaine association, abolishes the acquired conditioned reinforcing properties of the drug-associated stimulus and thus its impact on the learning of a new cocaine-seeking response. Furthermore, we show that reconsolidation of CS-fear memories also requires Zif268 in the amygdala. These results demonstrate that appetitive CS-drug memories undergo reconsolidation in a manner similar to aversive memories and that this amygdala-dependent reconsolidation can be disrupted to reduce the impact of drug cues on drug seeking.
Anmerkungen

Nothing has been marked as a citation.

Sichter
(Graf Isolan) Singulus

[3.] Jm/Fragment 004 19 - Diskussion
Zuletzt bearbeitet: 2014-01-12 21:48:59 Graf Isolan
Fragment, Gesichtet, Jm, KomplettPlagiat, SMWFragment, Schutzlevel sysop, Wang et al 2008

Typus
KomplettPlagiat
Bearbeiter
Hindemith
Gesichtet
Yes
Untersuchte Arbeit:
Seite: 4, Zeilen: 19-25
Quelle: Wang et al 2008
Seite(n): 5602, Zeilen: r.col: 14ff
Morphine CPP is persistently disrupted when anisomycin, a protein synthesis inhibitor, is administered after a conditioning session (Milekic et al., 2006). When mice previously conditioned for cocaine place preference are re-exposed to cocaine in the drug-paired compartment after systemic administration of SL327, an inhibitor of ERK (extracellular signal-regulated protein kinase) activation, CPP response is abolished (Valjent et al., 2006). Together, drug-related memory can be inhibited or erased by interrupting its reconsolidation process. Morphine CPP is persistently disrupted when anisomycin, a protein synthesis inhibitor, is administered after a conditioning session (Milekic et al., 2006). When mice previously conditioned for cocaine place preference are re-exposed to cocaine in the drug-paired compartment after systemic administration of SL327 [α-[amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl) benzeneacetonitrile], an inhibitor of ERK (extracellular signal-regulated protein kinase) activation, CPP response is abolished (Valjent et al., 2006a). Together, drug-related memory can be inhibited or erased by interrupting its reconsolidation process.
Anmerkungen

The source is not mentioned here, only on the next page in a different context.

Sichter
(Hindemith) Agrippina1


vorherige Seite | zur Übersichtsseite | folgende Seite
Letzte Bearbeitung dieser Seite: durch Benutzer:Graf Isolan, Zeitstempel: 20140113074753
Nutzung von Community-Inhalten gemäß CC-BY-SA , sofern nicht anders angegeben.