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| Untersuchte Arbeit: Seite: 10, Zeilen: 10-15 |
Quelle: Neill et al 2010 Seite(n): 1 (electronic version), Zeilen: right col. 3-12 |
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| Therefore, the application of aCGH has created a paradigm shift in genetics that has moved the description and discovery of genetic conditions from the "phenotype-first" approach, in which patients exhibiting similar clinical features are identified prior to the discovery of an underlying aetiology, to a "genotype-first" approach, in which a collection of individuals with similar copy-number imbalances can be examined for common clinical features (Neill 2010).
56. Neill N.J., et al., Comparative analysis of copy number detection by whole-genome BAC and oligonucleotide array CGH. Mol Cytogenet, 2010. 3: p. 11. |
Furthermore, the application of aCGH has created a paradigm shift in genetics that has moved the description and discovery of genetic conditions from the “phenotype-first”
approach, in which patients exhibiting similar clinical features are identified prior to the discovery of an underlying etiology, to a “genotype-first” approach, in which a collection of individuals with similar copy-number imbalances can be examined for common clinical features [15]. 15. Shaffer LG, Theisen A, Bejjani BA, Ballif BC, Aylsworth AS, Lim C, McDonald M, Ellison JW, Kostiner D, Saitta S, Shaikh T: The discovery of microdeletion syndromes in the post-genomic era: review of the methodology and characterization of a new 1q41q42 microdeletion syndrome. Genet Med 2007, 9:607-616. |
Although nearly identical, nothing has been marked as a citation. Since the reference has been changed to Neill 2010, it is more probable that this piece has been taken from Papa 2010 (see Mmu/Fragment_010_10). |
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