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BauernOpfer
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SleepyHollow02
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Untersuchte Arbeit:
Seite: 11, Zeilen: 20-33
Quelle: Delcenserie et al 2008
Seite(n): 39, Zeilen: right col, last paragraph
1.8. The mucosal immune system

Most of our encounters with antigens or infectious agents occur at mucosal surfaces, which include the surface lining the gastrointestinal, respiratory and genitourinary tracts (Delves and Roitt 2000). Since nutrients are usually absorbed orally, they are thus ideally suited to influence the immune response at the “mucosal frontier” of the gastrointestinal tract, representing more than 300 m2. Well known for its nutrition function (digestion of food and the assimilation of the nutrients), the intestinal system is also able to protect us from the pathogenic microbes. It contains more than 100 million neurons, secretes at least 20 neurotransmitters identical to those produced by the brain (serotonin, noradrenalin, dopamine, etc.), produces 70 to 85 % of the immune cells of the organism, lodges 100 000 billion bacteria. All these compounds, present locally, are in relationship to the whole of the organism (Delcenserie et al 2008). Although the immune response of the intestinal mucosa exhibits several features in common with the immune responses produced by other organs, it is characterized by certain distinctive [properties.]

2. The mucosal immune system

Most of our encounters with antigens or infectious agents occur at mucosal surfaces, which include the surface lining the gastrointestinal, respiratory and genitourinary tracts (Delves and Roitt, 2000). Since probiotics are usually absorbed orally, they are thus ideally suited to influence the immune response at the “mucosal frontier” of the gastrointestinal tract, representing more than 300 m2.

Well known for its nutrition function (digestion of food and the assimilation of the nutrients), the intestinal system is also able to protect us from the pathogenic microbes. It contains more than 100 million neurons, secretes at least 20 neurotransmitters identical to those produced by the brain (serotonin, noradrenalin, dopamine...), produces 70 to 85 % of the immune cells of the organism, lodges 100 000 billion bacteria. All these compounds, present locally, are in relationship to the whole of the organism. Although the immune response of the intestinal mucosa exhibits several features in common with the immune responses produced by other organs, it is characterized by certain distinctive properties.

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