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VroniPlag Wiki


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Graf Isolan
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Untersuchte Arbeit:
Seite: 25, Zeilen: 4-9
Quelle: Pan 1996
Seite(n): 22, Zeilen: 13-19
In summary, the Xenopus oocyte system has the advantage that channels, receptors and transporters can rapidly be expressed and identified by their electrophysiological properties. Once cDNA clones have been isolated, oocytes are an excellent system for correlating structure with function using a combination of molecular biological and electrophysiological techniques and analyzed both biochemically and electro physiologically in an in vivo situation. In summary, the Xenopus oocyte system has the advantage that channels, receptors and transporters can be rapidly expressed and analyzed both biochemically and

electrophysiologically in an in vivo situation. The system can be used quite effectively as an assay for the functional cloning of channels that have only been identified by their electrophysiological properties. Once cDNA clones have been isolated, oocytes are an excellent system for correlating structure with function using a combination of molecular biological and electrophysiological techniques.

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